Common Artificial Sweetener Xylitol Linked to Higher Risk of Heart Attacks and Cardiovascular Events
New research has linked the common artificial sweetener xylitol to a higher risk of heart attacks and other cardiovascular events. Xylitol is widely used in sugar-free gum, candies, and baked goods marketed as healthier alternatives.
The common artificial sweetener xylitol is associated with a higher risk of heart attacks and other cardiovascular events, according to research highlighted by Healthline in September 2026.
Xylitol is found in many products marketed as healthier alternatives to sugar, including sugar-free gum, candies, mints, and some baked goods. It is also used in oral care products like toothpaste and mouthwash because of its benefits for dental health.
The new research found that people with higher levels of xylitol in their blood had a significantly elevated risk of major cardiovascular events, including heart attacks and strokes. The study followed a large group of adults over several years and tracked cardiovascular outcomes.
Researchers believe xylitol may promote platelet aggregation, meaning it could make blood cells more likely to clump together and form clots. Blood clots are a primary cause of heart attacks and strokes.
"This does not mean people need to throw out their sugar-free gum," said one cardiologist who reviewed the findings. "But it is a signal that we need to look more carefully at these sweeteners."
The findings add to growing scrutiny of artificial sweeteners. Earlier research raised concerns about erythritol, another sugar alcohol used in many of the same products. Both xylitol and erythritol are often promoted as safe alternatives to sugar for people managing diabetes or trying to reduce calorie intake.
The study's authors say more research is needed to confirm the link and to understand the mechanism. They are calling for additional clinical trials.
In the meantime, health experts say people who are concerned about cardiovascular risk should discuss their diet with a doctor, including their use of products containing xylitol.
